Office in Mesa
  • Areas of Practice:
  • Bariatric Medicine / Surgery

Dr. Gary Knighton

About Gary Knighton, D.O.

Dr. Knighton, a long standing member of the Obesity Medicine Association (formerly the American Society of Bariatric Physicians) uses a multi-faceted approach, combining a balance of nutrition, activity, proper vitamin supplementation, and medications to help his patients shed the extra weight.

Dr. Knighton believes that making life changes can be downright enjoyable, when your support team is the staff at Arizona Medical Weight Loss.

“When you come in for your visit, regardless of how you’re feeling, we promise you’ll leave with a smile on your face, feeling better about yourself, and looking great,” he says.

At Arizona Medical Weight Loss, you can have it all. From individualized weight-control programs, including medications, vitamin injections, to diet and exercise plans.

Doctor Info

Professional Memberships

  • Obesity Medicine Association
  • American Medical Association
  • American Osteopathic Association
  • Arizona Osteopathic Medical Association

Honors & Awards

  • Dr. Knighton has been ranked #1 for 10 consecutive years by Ranking Arizona as the best physician for weight loss management/non-surgical in all of Arizona.
  • Dr. Knighton was also ranked in the top 3 in Arizona for cosmetic treatment/non-surgical for the past 10 years.

At Arizona Medical Weight Loss, you can have it all. From individualized weight-control programs, including medications and vitamin injections, to nutritional guidance. Plus you can have aesthetic procedures, chemical peels, permanent cosmetic applications — the works. You’ll not only love the results, you’ll enjoy the process. That’s how we’re different: at Arizona Medical Weight Loss.

Weight Loss

  • Individualized Program
  • Medications
  • Tirzepatide weekly injections
  • Activated B-12 Injections
  • Lipotropic Injections
  • Eat/Exercise According to Blood Type
  • Ketogenic Diet

Aesthetic Procedures

  • Botox®
  • Dysport®
  • Juvéderm®
  • Volbella®
  • Voluma®
  • Vollure®
  • Defyne®
  • Kysse®
  • Lyft®
  • Refyne®
  • Contour®
  • Chemical Peels

Other Services

  • ZO®
  • Medical Latisse ®
  • Testosterone replacement therapy for men
Our Office
Phone: (480) 539-1855
Monday: 8:30 AM - 5:00 PM
Tuesday: 8:30 AM - 5:00 PM
Wednesday: 8:30 AM - 5:00 PM
Thursday: 8:30 AM - 5:00 PM
Friday: 8:00 AM - 5:00 PM
Saturday: Closed
Sunday: Closed

Dr Knighton and his team have been literally a lifesaver.

My weight-loss journey has been a struggle for several years. One of the struggles has been finding the right doctor. I have heard from too many doctors that it’s all about calories in and calories out. We all know it’s not. Dr Knighton was the first doctor who educated me about the body. Losing weight with science behind me has made the usual yo‐yo experience easier to understand and work with. At no time did he judge me if I gained weight or didn’t lose as much as I wanted from appointment to appointment.

I have lost over 200 lbs. since I started working with him and his staff and my life has changed for the better.

I believe I would have had serious medical complications if I had not lost the weight. I still have those last troublesome 30 lbs. to lose, but I am confident that I will achieve my goals with the help and support of him and his team.

Chuck B.

I have been a patient of Dr Knighton’s practice for over 10 years and I would not go anywhere else for weight loss or aesthetic procedures. I trust them to always do what is best for my health and for looking my best naturally. In these past years I have lost over 40 lbs. and maintained my lower weight consistently and safely. I would highly recommend them to anyone seeking help with safe and effective weight loss and wanting to look their best. Dr. Knighton’s P.A. listened to my concerns and is careful to administer products that will enhance softly and gracefully. The office staff is all very nice and efficient keeping appointments running pretty much on time. They stay on top of their charts to ensure patients are keeping up with required blood tests and physicals, and while their prices may be bit higher than some, the peace of mind knowing they are practicing in a safe manner makes it worth the difference.


Lisa M.

I have been Dr. Knighton’s patient for 5 years. Dr. Knighton and his staff are amazing and Dr. Knighton is so knowledgeable and has the ability to explain how metabolism works in a way that is simple to understand. He helped me not only lose my weight, but he has helped me stay there, and I can proudly say that I have lost my weight for the last time in my life. I have been to other weight loss programs in the valley and no one comes close to the expertise, professionalism, caring attitude and success that Dr. Knighton’s office provides. As I have told my friends and family, don’t waste your time and money anywhere else. They have all seen Dr. Knighton and every one of them have reached their goal and have maintained it like I have. Dr. Knighton, you and your staff are literally the best! Thank you!


Brenda C.

Dr. Knighton is awesome! Making an appointment is always simple and he is willing to spend whatever time is needed to answer your questions, listens to your situation and works with what you are comfortable with, many options for weight loss programs. His staff is just as amazing! EVERYONE is friendly and so helpful to get you in and out as quickly as possible. I love not having to make an appointment every week for my B12 injections. They do not bill insurance but pricing is reasonable and they offer package options which make it a more affordable. I definitely recommend Dr. Knighton and his awesome staff!


Erika S.

I have had the best experience at Dr. Knighton’s office! Everyone cares about you, they really do. It starts with Dr. Knighton, he takes his time getting to know you and about your issues. Then Kelly, Dr. Knighton’s P.A., and the other wonderful ladies are also just as caring! Meanwhile, while liking the office and the people so much; I have done very well at losing and maintaining my weight!! I couldn’t have done that without all of their support! I feel so much better about myself and everyone can tell.


Anna H.